Custom Synthesis (Chemicals)

Synthesis of Reference Standards, Screening Compounds, APIs Metabolites

At ACC Corporation, we offer advanced synthesis of intermediates, building blocks, reference compounds, pharmacological standards / starting materials, and derivatives of lead compounds. If you are looking for products not available commercially, with specific composition or in unique quantities, we can make them for you. We will work with you to find the best solution, be it reproduction of published methods, new routes for your products or simple synthetics procedures to be followed. Strict client confidentiality is ensured for all our projects. Listed below are our areas of specialization.
 
Discovery Research
Cores
We have a collection of about 5000 building blocks. These include active intermediates and medicinal chemistry cores with over 2-3 points of diversity. They cover most of the functional groups such as primary and secondary amines, acids, aldehydes and polyfunctional building blocks. They can be used for both solid and solution phase synthesis. They are ideal for the design of new template, scaffolds or fragment based screening.
 
Confidentiality is ensured for all projects. All products have purity of 95% or more.
 
Please send us your inquiries on custom synthesis of compounds to customerservice@acccorporation.com%
 
Reference Standards
 
We carry one of the largest sets of reference compounds in our catalog. These are available to you for immediate use. We can also custom make them for you based on your requirements. Our library of reference standards includes drug substances, excipients, impurities, degradation products, performance calibrators and reagents. All of the custom products come with full chemical certification including HPLC, NMR as well as LC-MS.
 
Confidentiality is ensured for all projects. All products have purity of 95% or more.
 
Please send us your inquiries on custom synthesis of compounds to customerservice@acccorporation.com%
 
Impurities
 
We do synthesis of drug related impurities and metabolites. Depending on your requirements, they can be made in the mg to gm scale. You can give us the synthetic routes or we could do it for you. Impurities are isolated by HPLC and characterized by NMR, MS and FTIR or LC-MS/MS etc to get the full characterization of the compound.
 
Confidentiality is ensured for all projects. All products have purity of 95% or more.
 
Please send us your inquiries on custom synthesis of compounds to customerservice@acccorporation.com%
 
Library Synthesis
 
ACC Corporation offers unique libraries and building blocks. These include scaffold based libraries as well as libraries focused on specific targets such as Kinases, GPCRs, Proteases, Ion Channels, CNS and NH receptors. We can also make custom libraries based on your scaffolds or the scaffolds offered by us, specific to targets to meet your research requirements. The custom libraries are verified by HPLC and NMR tests.
 
Confidentiality is ensured for all projects. All products have purity of 95% or more.
 
All products come with full documentation (HNMR, HPLC, MS, LC-MS, COA and MSDS are included; 13CNMR and IR are provided, if required). Weekly reports on the progress of the synthesis are sent to you to keep you updated on the status of the development.
 
Please send us your inquiries on custom synthesis of compounds to customerservice@acccorporation.com%
 
Areas of Expertise
 
Our areas of expertise include:
  • Kinases
  • Reference Standards
  • Anti-HIV
  • Anti-Cancer
  • Anti-Viral
  • Anti-Bacterial
  • GPCRs
  • Inhibitors
  • Chiral Synthesis
  • Antibodies
Process and Scale-up Research
Types of Projects
We undertake the following types of projects:
  • Heterocyclic Chemistry
  • Multi-step Synthesis
  • Microwave Parallel Synthesis
  • Parallel Synthesis
  • Synthesis of Small Functionalized Molecules
  • Synthesis of Small Focused Libraries
  • Synthesis of Building Blocks, Cores and Screening Compounds
  • Synthesis of GMP Impurities
Types of Reactions
 
Our portfolio of reactions includes:
 
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FTE
ACC Corporation, and its subsidiaries, offer FTEs (Full Time Equivalent) scientists (Ph.D., MS, BS-level chemists) to our customers for bioactive molecule synthesis, scale up and process research & development. Our hardworking and experienced chemists can save you time and money while minimizing risks and costs in the early stages of your research and development projects.
 
Scientists in our facilities are able to help in several areas that include:
  • Lead generation and optimization
  • Design and synthesis of analogs to support structure-activity relationship studies
  • Rapid synthesis of focused libraries
  • Synthesis of reference compounds and metabolites
  • Preparation of scaffolds and building blocks
The ACC Corporation Medicinal Chemistry teams operate in modern and well equipped facilities designed for synthesis, analysis, and purification activities. Supported by a secure IT infrastructure, our scientists have online access to chemical literature to facilitate rapid conversion of ideas to experiments.
 
 
Custom Synthesis (Chemicals) 

Our portfolio of reactions (continued):

Confidentiality is guaranteed on all projects.
 
Please send us your inquiries on Custom Synthesis of compounds to